Amazing Spider-Man #300 — Signed Todd McFarlane, CGC 9.6

Amazing Spider-Man #300 is the issue in which Venom arrives in full: published in May 1988, written by David Michelinie and drawn by Todd McFarlane, it turned a lingering threat into the defining antagonist of the era and gave the series one of its most reproduced covers — Spider-Man mid-leap against a field of red and black.

This copy carries McFarlane's signature and is certified CGC 9.6 in a Signature Series holder, a combination that joins the artist most associated with Venom's visual identity to a high-grade example of the book itself. McFarlane's work on the title redefined the way Spider-Man moved on the page, and his signature on a 9.6 copy of #300 is the configuration collectors of the run look for. Few Marvel issues of the late 1980s carry the same structural weight: a first full appearance, a landmark creative run and a cover that has become part of the visual culture of the character.